Effects of X-ray Radiation on Physical Appearance and Large Intestines of Swiss Webster Mice (Mus musculus) Linn.

This study was conducted to identify the effects of X-ray radiation on Swiss Webster mice (Mus musculus). It focused on four major points: (1) Determine the changes in body weight; (2) Determine the presence of hair loss; (3) Determine the presence of erythema; (4) Examine histological changes in the large intestine of Swiss Webster mice (Mus musculus). In answering these four statements, the researchers used the experimental design. The method was further used in determining the effects of x-ray radiation on Swiss Webster mice (Mus musculus). Twenty Swiss Webster Mice of about the same age were used as experimental animals. They were divided equally to comprise four different treatments including one control. Each treatment as well as the control consists of five Swiss Webster Mice that serves as replicates. Based on the results, irradiated Swiss Webster mice experienced weight loss and death after ten days of observation. Irradiated Swiss Webster mice experienced erythema. Irradiated Swiss Webster mice experienced hair loss. Histological examination of the large intestines of treatment 1 and 2 reveals presence of fluid in the lymphatic nodule, showing breakage in serosal wall, presence of hemorrhage in the mucosa, misaligned outer longitudinal muscle layer, inflammatory cells and enlarged inflammatory cells

 

Keywords – Swiss Webster mice (Mus  musculus), X-ray radiation exposure, Effects of radiation, Physical appearance, Weight Loss, Hair Loss, Erythema, Histological Examination.