The Inhibitory Effect of Paragis (Eleusine Indica) Stem Extract on the Growth of Staphylococcus Aureus and Escherichia Coli

Eleusine indica Linn Gaertn.from the family, Poaceae, generally known as Paragis, is native in the tropics and subtropical regions. It has a broad tolerance to a wide array of environmental settings, but its somatic growth is ominously reduced during dry seasons. This study is intended to validate the traditional use of eleusine indica stem as an effective antimicrobial agent, thus giving the common practice a scientific base. This study focused on the zone of inhibition and it is phytochemical components. Confirmatory test was conceded out on the stem parts of eleusine indica to obtain ethnomedicinal claims on the part. The ethanolic whole plant extract was obtained utilizing percolation for seven days and yielded 1.16% based on four replicates of 10 gram-samples. Confirmatory tests were done for the presence of Alkaloids, Flavonoids, and Tannin. The organisms were then treated with different concentrations of Paragis ( eleusin inidica ) extract, 100%,75%, 50%, 25%, negative and positive control. Extracts from the stems showed no inhibition zones with 0 diameters against MRSA S.aureus and E.coli. Therefore the null hypothesis, which says that “ Eleusine indica (Paragis) stem extract does not have significant inhibitory effects on the growth of S.aureus and e.coli” failed to be rejected. Thus, Eleusine indica extract is not a potential antibacterial agent against S.aureus and E. coli.

Keywords: alkaloids, flavonoids, tannins, antimicrobial, antibacterial agent